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The Repairing Epistemic Mistrust and Securing Engagement in Therapy (RESET) Study

A secondary data analysis on dropout and epistemic mistrust among adolescents diagnosed with major depressive disorder.

Dr Elizabeth Li presents the RESET study

The Repairing Epistemic Mistrust and Securing Engagement in Therapy (RESET) Study

Many adolescents leave mental health treatment early, often because they feel therapy is not helping. This project focuses on a subgroup of adolescents who end therapy feeling dissatisfied, aiming to understand the relational and psychological processes that may contribute to these experiences.

The secondary data analysis study explores why some young people disengage from therapy and how difficulties in trust and communication in adolescents—particularly in therapeutic moments of tension or disconnect—might influence a young person's decision to stop therapy.

By analysing recorded therapy sessions, the research will examine how these challenges unfold and whether specific therapeutic responses may help repair moments of strain and improve engagement.

The findings aim to support therapists working with adolescents who are at risk of disengaging from care.

Co-Principal Investigators: Dr Elizabeth Li (University College London and Anna Freud Centre) & Dr Sally O’Keeffe (Newcastle University)

Funder: British Association for Counselling and Psychotherapy (BACP)

Study benefits

writing_at_desk

Identifies signs of epistemic mistrust and trust in therapy sessions

Develops a coding tool to identify signs of epistemic mistrust and trust in therapy sessions, with direct insights from our young people advisory panel.

Nature assisted therapy

Explores how epistemic mistrust influences adolescent therapy dropout

Improves understanding of why adolescents disengage from therapy, particularly how epistemic mistrust—difficulty trusting and learning from others—may shape their experience of therapy and influence their decision to leave.

Commitment to Diversity 3

Supports development of trust-focused, dropout-prevention therapies

Contributes to more responsive and adaptive therapeutic approaches that build or repair trust and prevent dropout.

Intro Module (2)

Enhances therapist training to better support at-risk adolescents

Informs training and supervision of therapists, helping professionals better support adolescents at risk of disengaging from mental health care.

Relevant publications:

Li, E., Midgley, N., Campbell, C., & Luyten, P. (2025). A theory-building case study of resolving epistemic mistrust and developing epistemic trust in psychotherapy with depressed adolescents. Psychotherapy research, 1–19. Advance online publication.

Li, E., Midgley, N., Luyten, P., Sprecher, E., & Campbell, C. (2022). Mapping the journey from epistemic mistrust in depressed adolescents receiving psychotherapy. Journal of Counseling Psychology, 69(5), 678–690.

O’Keeffe, S., Martin, P., & Midgley, N. (2020). When adolescents stop psychological therapy: Rupture-repair in the therapeutic alliance and association with therapy ending. Psychotherapy, 57(4), 471–490.

O’Keeffe, S., Martin, P., Target, M., & Midgley, N. (2019). ‘I just stopped going’: A mixed methods investigation into types of therapy dropout in adolescents with depression. Frontiers in Psychology, 10, 75.

O’Keeffe, S., Martin, P., Goodyer, I., Kelvin, R., Dubicka, B., IMPACT Consortium, & Midgley, N. (2019). Prognostic implications for depressed adolescents who drop out of psychological treatment during a randomised controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 58(10), 983-992.

O’Keeffe, S., Martin, P., Goodyer, I., Wilkinson, P., IMPACT Consortium, & Midgley, N. (2018). Predicting dropout in adolescents receiving therapy for depression. Psychotherapy Research, 28(5), 708-721.

For more information, please contact elizabeth.li@ucl.ac.uk and sally.o'keeffe@newcastle.ac.uk.

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