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  • Evaluation of reliable improvement rates in depression and anxiety at the end of treatment in adolescents

    The aim of this study was to consider how many adolescents report reliable improvement in anxiety, depression and comorbid depression and anxiety by end of treatment. Authors: Edbrooke-Childs, J., Wolpert, M., Zamperoni, V., Napelone, E., Bear, H. (2018).

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  • Strategies not accompanied by a mental health professional to address anxiety and depression in children and young people: a scoping review of range and a systematic review of effectiveness

    This Review reports on a scoping review followed by a systematic review to consider interventions designed to address or manage depression or anxiety in children and young people up to the age of 25 years without the need to involve mental health professionals. Authors: Wolpert, M., Dalzell, K., Ullman, R., Garland, L., Cortina, M., Hayes, D., Patalay, P., & Law, D. (2018).

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  • Toward precision therapeutics: general and specific factors differentiate symptom change in depressed adolescents

    The longitudinal course of multiple symptom domains in adolescents treated for major depression is not known. This study aims to reveal the temporal course of general and specific psychopathology factors, including potential differences between psychotherapies, which may aid therapeutic decision-making. Authors: Aitken, M., Haltigan, J., Szatmari, P., Dubicka, B., Fonagy, P., Kelvin, R., Midgley, N., Reynolds, S., Wilkinson, P. & Goodyer, I. (2020).

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  • The therapeutic process in psychodynamic therapy with children with different capacities for mentalizing

    The aim of this study was to explore the therapeutic process in psychodynamic therapy with school-age children with different kinds of difficulties and mentalizing profiles. Authors: Ramires, V., Carvalho, C., Goodman, G., Midgley, N. & Polli. R. (2020).

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  • Association between quetiapine use and self-harm outcomes among people with recorded personality disorder in UK primary care: a self-controlled case series analysis

    This paper aims to examine associations between periods of quetiapine prescribing and self-harm events in people with personality disorder. Authors: Hayes, J. F., Hardoon, S., Deighton, J., Viding, E., & Osborn, D. P. J. (2022).

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  • Brief Educational Workshops in Secondary Schools Trial (BESST): protocol for a school-based cluster randomised controlled trial of open-access psychological workshop programme for 16–18-year-olds

    One intervention that has been shown to be feasible to reducing stress, anxiety and depression in adolescents is a school-based stress workshop programme for 16–18-year-olds (herein called DISCOVER). The next step is to rigorously assess the effectiveness, and cost-effectiveness, of the DISCOVER intervention in a fully powered cluster randomised controlled trial. Authors: Lisk, S., Carter, B., James, K., Stallard, P., Deighton, J., Yarrum, J., Fonagy, P., Day, C., Byford, S., Shearer, J., Weaver, T., Sclare, I., Evans, C., Farrelly, M., Ho, PC., Brown, J. (2022).

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  • Trajectories of change in general psychopathology levels among depressed adolescents in short-term psychotherapies

    This paper aims to identify and describe trajectories of change in general psychopathology (p) levels among depressed adolescents who received one of three types of short-term therapies (namely Cognitive–Behavioural Therapy, Short-Term Psychoanalytic Psychotherapy, and a Brief Psychosocial Intervention). Authors: Fiorini, G., Saunders, R., Fonagy, P., The IMPACT Consortium, Midgley, N. (2022).

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  • Connecting over the internet: establishing the therapeutic alliance in an internet-based treatment for depressed adolescents

    This study uses data collected during a pilot evaluation of a psychodynamic internet-based therapy for depressed adolescents. The adolescents had instant-messaging chats with their therapists once a week, over 10 weeks. Authors: Mortimer, R., Somerville, M.P., Mechler, J., Lindqvist, K., Leibovich, L., Guerrero-Tates, B., Edbrooke-Childs, J., Martin, P., & Midgley, N. (2022).

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  • Trajectories of change of youth depressive symptoms in routine care: shape, predictors, and service-use implications

    This study used multilevel modeling to examine the average trajectory of change and the factors associated with change in depressive symptoms in a large sample of youth seen in routine mental health care services in England. Authors: Napoleone, E., Evans, C., Patalay, P., Wolpert, M., Edbrooke-Childs, J. (2019).

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