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  • Association between quetiapine use and self-harm outcomes among people with recorded personality disorder in UK primary care: a self-controlled case series analysis

    This paper aims to examine associations between periods of quetiapine prescribing and self-harm events in people with personality disorder. Authors: Hayes, J. F., Hardoon, S., Deighton, J., Viding, E., & Osborn, D. P. J. (2022).

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  • Brief Educational Workshops in Secondary Schools Trial (BESST): protocol for a school-based cluster randomised controlled trial of open-access psychological workshop programme for 16–18-year-olds

    One intervention that has been shown to be feasible to reducing stress, anxiety and depression in adolescents is a school-based stress workshop programme for 16–18-year-olds (herein called DISCOVER). The next step is to rigorously assess the effectiveness, and cost-effectiveness, of the DISCOVER intervention in a fully powered cluster randomised controlled trial. Authors: Lisk, S., Carter, B., James, K., Stallard, P., Deighton, J., Yarrum, J., Fonagy, P., Day, C., Byford, S., Shearer, J., Weaver, T., Sclare, I., Evans, C., Farrelly, M., Ho, PC., Brown, J. (2022).

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  • The Depression: Online Therapy Study (D:OTS) – a pilot study of an internet-based psychodynamic treatment for adolescents with low mood in the UK, in the context of the COVID-19 pandemic

    This pilot study examined the feasibility, acceptability and effectiveness of an English-language adaptation of internet-based psychodynamic treatment for depressed adolescents, undertaken during the COVID-19 pandemic in the UK. Authors: Midgley, N., Guerrero-Tates, B., Mortimer, R., Edbrooke-Childs, J., Mechler, J., Lindqvist, K., Hajkowski, S., Leibovich, L., Martin, P., Andersson, G., Vlaescu, G., Lilliengren, P., Kitson, A., Butler-Wheelhouse, P., & Philips, B. (2021).

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  • Unpacking the active ingredients of internet-based psychodynamic therapy for adolescents

    This paper aims to explore the techniques used in chat sessions in an iPDT program for depressed adolescents, and to investigate whether they predicted improvement in depression symptoms. Authors: Leibovich, L., Mechler, J., Lindqvist, K., Mortimer, R., Edbrooke-Childs, J., Midgley, N. (2022).

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  • Trajectories of change in general psychopathology levels among depressed adolescents in short-term psychotherapies

    This paper aims to identify and describe trajectories of change in general psychopathology (p) levels among depressed adolescents who received one of three types of short-term therapies (namely Cognitive–Behavioural Therapy, Short-Term Psychoanalytic Psychotherapy, and a Brief Psychosocial Intervention). Authors: Fiorini, G., Saunders, R., Fonagy, P., The IMPACT Consortium, Midgley, N. (2022).

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  • Connecting over the internet: establishing the therapeutic alliance in an internet-based treatment for depressed adolescents

    This study uses data collected during a pilot evaluation of a psychodynamic internet-based therapy for depressed adolescents. The adolescents had instant-messaging chats with their therapists once a week, over 10 weeks. Authors: Mortimer, R., Somerville, M.P., Mechler, J., Lindqvist, K., Leibovich, L., Guerrero-Tates, B., Edbrooke-Childs, J., Martin, P., & Midgley, N. (2022).

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  • Trajectories of change of youth depressive symptoms in routine care: shape, predictors, and service-use implications

    This study used multilevel modeling to examine the average trajectory of change and the factors associated with change in depressive symptoms in a large sample of youth seen in routine mental health care services in England. Authors: Napoleone, E., Evans, C., Patalay, P., Wolpert, M., Edbrooke-Childs, J. (2019).

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  • Predicting mental health improvement and deterioration in a large community sample of 11- to 13-year-olds

    This study examined rates of reliable improvement/deterioration for children in a school sample over time. N = 9074 children from 118 secondary schools across England provided self-report mental health (SDQ), quality of life and demographic data (age, ethnicity and free school meals (FSM) at baseline and 1 year and self-report data on access to mental health support at 1 year). Authors: Wolpert, M., Zamperoni, V., Napaleone, E., Patalay, P., Jacob, J., Fokkema, M., Promberger, M., Costa da Silva, L., Patel, M., Edbrooke-Childs, J. (2019).

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  • School-based intervention study examining approaches for well-being and mental health literacy of pupils in Year 9 in England: study protocol for a multischool, parallel group cluster randomised controlled trial (AWARE)

    This protocol describes a three-arm, parallel group cluster randomised controlled trial, investigating the effectiveness and cost-effectiveness of two interventions, alongside a process and implementation evaluation, to improve mental health and well-being of Year 9 pupils in English secondary schools. Authors: Hayes, D., Moore, A., Stapley, E., Humphrey, N., Mansfield, R., Santos, J., Ashworth, A., Patalay, P., Bonin, E., Boehnke, J. R., Deighton, J. (2019).

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