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  • Reducing self-harm in adolescents: Pooled treatment effects, study, treatment and participant moderators

    This individual participant data (IPD) meta-analysis of randomized controlled trials (RCTs) aimed to provide robust estimates of therapeutic intervention effects and explore which treatments are best suited to different subgroups.

    Authors: Wright-Hughes, A., Farrin, A. J., Fonagy, P., et al.

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  • Intranasal oxytocin increases breast milk oxytocin, but has a reduced effect in depressed mothers: A randomized controlled trial

    In a double-blind, randomized controlled trial, we assessed endogenous oxytocin (OT) concentrations first in the breast milk of new mothers at baseline, and second following the administration of exogenous OT compared to a placebo delivered via a nasal spray.

    Authors: Lindley Baron-Cohen, K., L., Fearon, P., Feldman, R., et al.

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  • Predicting criminal offence in adolescents who exhibit antisocial behaviour: A machine learning study using data from a large randomised controlled trial of multisystemic therapy

    In this study, we developed machine learning models that predict offending status with good accuracy and show interpretable machine learning analyses can complement models to inform clinical decision-making.

    Authors: Suh, J. W., Saunders, R., Simes, E., et al.

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  • Reducing self-harm in adolescents: The RISA-IPD individual patient data meta-analysis and systematic review

    In this study, we examined raw data from multiple clinical trials to find out which therapeutic treatments are most effective at preventing self-harm repetition when young people present to services having harmed themselves.

    Authors: Cottrell, D., Wright-Hughes, A., Farrin, A., et al.

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  • Therapist and treatment credibility in treatment outcomes: A systematic review and meta-analysis of clients' perceptions in individual and face-to-face psychotherapies.

    This study aimed to examine the relationship between perceived treatment and therapist credibility and treatment outcomes, while considering the timing of the credibility assessment as a potential moderator.

    Authors: Kumpasoğlu, G. B., Campbell, C., Saunders, R., et al.

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  • Twelve-month outcomes and comparative costs of internet-delivered psychodynamic therapy versus cognitive-behavioral therapy for adolescent depression: a randomized controlled trial.

    This study investigated different types of internet-based psychotherapy.

    Authors: Lindqvist, K., Mechler, J., Peristera, P., et al.

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  • Randomized trial of feedback-informed online psychodynamic therapy for depressed adolescents

    This study evaluated online psychodynamic therapy for adolescents with depression, finding improvements in mood, anxiety, and emotion regulation for completers, but recruitment challenges under new EU rules led to early discontinuation.

    Authors: Philips, B., Mechler, J., Uckelstam, C.-J., et al.

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  • Self-criticism and dependency in adolescents with depression: Associations with clinical features and psychological functioning

    This study of 400+ clinically depressed adolescents found self-criticism linked to more severe mental health and relationship difficulties than dependency, with a gender-mismatch effect heightening anxiety and suicidal thoughts.

    Authors: Bai, Y., Midgley, N., Luyten, P.

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  • “I too deserve good”: A qualitative exploration of corrective relational experiences in psychodynamic therapy for depression

    This study examines corrective relational experiences in psychotherapy, identifying four common types and showing they support personal growth and strengthen therapeutic relationships, with lasting effects beyond treatment.

    Authors: Leibovich, L., Sadek, A., Ben David-Sela, T., et al.

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