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  • Mentalization-based treatment for antisocial personality disorder in males convicted of an offence on community probation in England and Wales: : a multicentre, assessor-blinded, randomised controlled trial

    This study aimed to evaluate the clinical and cost-effectiveness of MBT-ASPD compared with probation as usual in reducing aggressive behaviours from baseline to 12 months of follow-up.

    Authors: Fonagy, P., Simes, E., Yirmiya, K., et al.

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  • The impact of place-based approaches addressing mental health and substance use among adolescents: A systematic review of the literature

    In this study, we systematically appraised peer reviewed evidence assessing the impact of “place-based approaches” (PBAs) on mental health outcomes among adolescents.

    Authors: Rehill, N., Halvorsrud, K., Shand, J., et al.

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  • Bridging the gap: A qualitative study exploring the impact of the involvement of researchers with lived experience on a multi-site randomised control trial in the National Probation Service in England and Wales

    This study aimed to explore the value of involving researchers with lived experience of the criminal justice system as data collectors in the Mentalization for Offending Adult Males (MOAM), a multisite RCT.

    Authors: Simes, E., Butler, S., Allison, E., et al.

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  • Reducing self-harm in adolescents: Pooled treatment effects, study, treatment and participant moderators

    This individual participant data (IPD) meta-analysis of randomized controlled trials (RCTs) aimed to provide robust estimates of therapeutic intervention effects and explore which treatments are best suited to different subgroups.

    Authors: Wright-Hughes, A., Farrin, A. J., Fonagy, P., et al.

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  • Identifying subgroups of individuals based on their epistemic stance, attachment dimensions and childhood trauma: A latent profile analysis

    This study examines the interplay between epistemic stance, attachment dimensions, and childhood trauma in relation to specific demographic factors and mental health outcomes.

    Authors: Delamain, H., Saunders, R., Tanzer, M., et al.

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  • Intranasal oxytocin increases breast milk oxytocin, but has a reduced effect in depressed mothers: A randomized controlled trial

    In a double-blind, randomized controlled trial, we assessed endogenous oxytocin (OT) concentrations first in the breast milk of new mothers at baseline, and second following the administration of exogenous OT compared to a placebo delivered via a nasal spray.

    Authors: Lindley Baron-Cohen, K., L., Fearon, P., Feldman, R., et al.

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  • A service evaluation of the 6–8-week postpartum mental health check-up in Cheshire and Merseyside: Interim findings from a survey of GPs and health visitors

    This pilot case-control study aimed to detect novel candidate biomarkers, derived from non-invasive retinal imaging, as measures of vascular response to pregnancy and placental insufficiency.

    Authors: Lindley Baron-Cohen, K., Fonagy, P., & Roberts, D.

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  • Predicting criminal offence in adolescents who exhibit antisocial behaviour: A machine learning study using data from a large randomised controlled trial of multisystemic therapy

    In this study, we developed machine learning models that predict offending status with good accuracy and show interpretable machine learning analyses can complement models to inform clinical decision-making.

    Authors: Suh, J. W., Saunders, R., Simes, E., et al.

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  • Reducing self-harm in adolescents: The RISA-IPD individual patient data meta-analysis and systematic review

    In this study, we examined raw data from multiple clinical trials to find out which therapeutic treatments are most effective at preventing self-harm repetition when young people present to services having harmed themselves.

    Authors: Cottrell, D., Wright-Hughes, A., Farrin, A., et al.

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